The complex relationship of serum adiponectin to COPD outcomes.

Chest. 2011 Dec 29;
Yoon H, Li Y, Man SF, Tashkin D, Wise RA, Connett JE, Anthonisen NA, Churg A, Wright JL, Sin DD

ABSTRACT BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder with high risk of cardiovascular morbidity and mortality. Adiponectin is a hormone that has anti-inflammatory, anti-diabetic, and anti-atherogenic activities. We investigated the relationship of serum adiponectin to health outcomes in COPD. METHODS:We measured adiponectin levels in serum samples from participants of the Lung Health Study (LHS), who were smokers with mild to moderate airflow limitation. We determined the relationship of serum adiponectin to hospitalization and mortality using Cox proportional hazards model and to baseline lung function measurements and to bronchial reactivity using multiple regression methods. RESULTS:Serum adiponectin concentrations were inversely related to hospitalizations and mortality from coronary heart disease (hazard ratio, HR, 0.73; 95% CI, 0.62 to 0.86) and to cardiovascular disease (HR, 0.83; 95% CI, 0.73 to 0.94) and positively related to deaths from respiratory causes (HR, 2.09; 95% CI, 1.41 to 3.11). However, serum adiponectin concentrations were not significantly related to total mortality (HR, 1.10; 95% CI, 0.93 to 1.29) or cancer-related mortality (HR, 1.11; 95% 0.92 to 1.34). Serum adiponectin concentrations were significantly related to increased bronchial reactivity and an accelerated decline in lung function (both p

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Heart disease runs in my family - but I’m healthy
No description available
Mon, 26 Dec 2011 21:32:01 -0800
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Are Marital Problems Literally Bad for your Heart? - GoodTherapy.org (blog)

Are Marital Problems Literally Bad for your Heart?
GoodTherapy.org (blog)
“Marital disruption (ie, separation, divorce) and strain (ie, conflict, dissatisfaction) predict the development of CHD (coronary heart disease) and poor prognosis for heart patients,” said Timothy W. Smith of the Department of Psychology at the


Sat, 31 Dec 2011 18:59:15 GMT
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nimitta & bhavana: work in progress
Aśvaghoṣa is 12th in a line of 51 patriarchs linking the Buddha in India and Dogen in Japan, all of whom, according to Zen tradition, preached the primacy of sitting-meditation (ZA-ZEN; sitting- dhyāna). In the Zen teaching of Dogen, represented by the famous phrase “just sitting,” (SHIKAN-TAZA) the
Sun, 1 Jan 2012 02:04:00 CST
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Natural Antioxidant Supplements
As noted by Dr. Richard Anderson in his website http://www.cleanse.net/antioxidantformula.aspx, an effective natural antioxidant preparations must contain a broad spectrum of antioxidants. Dr. Anderson provides cogent reasons why a natural antioxidant supplement should contain a combination of antio
Sun, 1 Jan 2012 03:10:00 CST
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RT @SlowFoodMelb: Can we cut cancer and heart disease rates just by going vegan? - The Ecologist http://t.co/ey0RomG9
RT @SlowFoodMelb: Can we cut cancer and heart disease rates just by going vegan? - The Ecologist http://t.co/ey0RomG9
natasha_lila@twitter.com (Natasha)
Sat, 31 Dec 2011 09:18:36 +0000
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Safety and effectiveness of the Catania Polyzene-F coated stent in real world clinical practice: 12-month results from the ATLANTA 2 registry.

EuroIntervention. 2011 Dec 30; 7(9): 1062-8
Tamburino C, Capodanno D, Di Salvo ME, Sanfilippo A, Cascone I, Incardona V, Longo G, Giacoppo D, Capranzano P, Sgroi C, Ussia G, Monaco A, La Manna A

Aims: The pivotal ATLANTA first-in-man study showed the promising safety and efficacy profile of the novel Catania™ stent in a population with ~20% American College of Cardiology/American Heart Association (ACC/AHA) type C coronary lesions. The ATLANTA 2 registry was designed to evaluate the 12-month safety and efficacy of the Catania stent in a broader real world scenario. Methods and results: The ATLANTA 2 registry was a prospective, non-randomised, single-arm study of patients with symptomatic ischaemic heart disease and de novo lesions of native coronary arteries. A total of 300 patients (396 lesions) were recruited and 482 Catania stents were implanted. At 12 months, major adverse cardiac events were 8.8%, mainly driven by target lesion revascularisation (6.5%). Cardiac death and non-fatal myocardial infarction occurred in 2.5% and 0.7% of patients, respectively. Subacute definite or probable stent thrombosis was 0.7%. No late stent thrombosis was recorded. Compared with patients treated with drug-eluting stents or bare metal stents in the study period, those treated with Catania stents experienced similar outcomes at one year. Conclusions: The 12-month results of the ATLANTA 2 registry confirmed the positive results of the ATLANTA first-in-man trial in a more complex population. A randomised trial is needed to assess the comparative value of the Catania stent over currently-used drug-eluting stents or bare metal stents.

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Evening Chronicle (Newcastle, England) - YOUNG women can dramatically reduce […]
December 1, 2011 —

YOUNG women can dramatically reduce their risk of heart disease by eating oily fish, a study has found.

Those who ate oily fish each…
Thu, 01 Dec 2011 00:00:00 PST
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Sharon Kleyne Hour Power of Water Announces Growing World Blindness Rate Could be Preventable through Diet and Water

Sharon Kleyne interviews Alan Taylor, PhD, Laboratory for Nutrition and Vision Research, Tufts University.

(PRWeb December 30, 2011)

Read the full story at


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MRI scan ‘better’ for heart patients
A magnetic resonance imaging scan for coronary heart disease is better than the most commonly-used alternative, a major UK trial of heart disease patients has shown.
Wed, 28 Dec 2011 11:06:12 -0800
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Fibromyalgia, Malic Acid, apples

Filed Under heart disease | Comments Off

Tips To Help Prevent Heart Disease http://t.co/7i2juvle
Tips To Help Prevent Heart Disease http://t.co/7i2juvle
Jonhsmithlds@twitter.com (jonh Smitht )
Fri, 30 Dec 2011 09:35:12 +0000
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Heart diseases set to fall in India: Doctor - Thaindian.com
New Delhi, Dec 25 (IANS) There is good news on the health front. A leading cardiologist says incidents of heart disease in India are set to plateau in seven to eight years and then fall due to greater awareness about a healthy lifestyle and more effective …
2011-12-25T08:34:21Z
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Low vitamin D levels linked to diabetes, heart disease - My West Texas

Low vitamin D levels linked to diabetes, heart disease
My West Texas
By Dr. Stephen Ponder Heart disease is the No. 1 killer of Americans. There also has been a wealth of scientific studies linking low levels of vitamin D in the body and a higher risk for developing heart disease and death from heart disease in

and more »
Thu, 29 Dec 2011 17:30:15 GMT
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MRI Scans Better For Suspected Heart Disease Patients
In recent years, imaging techniques such as the most commonly used single-photon emission computed tomography (SPECT), have gradually replaced exercise treadmill tests for diagnosing heart disease. Now a five-year trial of over 750 heart disease patients conducted by the University of Leeds in the UK suggests that a more modern scanning method based on magnetic resonance imaging (MRI) is better …
Wed, 28 Dec 2011 05:30:31 -0800
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Fibromyalgia, Malic Acid, apples
Fibromyalgia : generalized musculoskeletal pain, aches, stiffness, and tenderness.
Fri, 30 Dec 2011 08:59:59 GMT
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Statins May Work to Reverse Heart Disease (Video) - Insidermedicine

PR Web

Statins May Work to Reverse Heart Disease (Video)
Insidermedicine
Taking maximal doses of cholesterol-lowering drugs known as statins can actually help reverse signs of cardiovascular disease, according to research published in the New England Journal of Medicine. Researchers from the Cleveland Clinic used ultrasound
Reversing Heart Disease and Preventing Heart Attacks over the Christmas Season San Francisco Chronicle (press release)

all 3 news articles »
Wed, 28 Dec 2011 22:01:30 GMT
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Glutathione-dependent reductive stress triggers mitochondrial oxidation and cytotoxicity.

FASEB J. 2011 Dec 27;
Zhang H, Limphong P, Pieper J, Liu Q, Rodesch CK, Christians E, Benjamin IJ

To investigate the effects of the predominant nonprotein thiol, glutathione (GSH), on redox homeostasis, we employed complementary pharmacological and genetic strategies to determine the consequences of both loss- and gain-of-function GSH content in vitro. We monitored the redox events in the cytosol and mitochondria using reduction-oxidation sensitive green fluorescent protein (roGFP) probes and the level of reduced/oxidized thioredoxins (Trxs). Either H(2)O(2) or the Trx reductase inhibitor 1-chloro-2,4-dinitrobenzene (DNCB), in embryonic rat heart (H9c2) cells, evoked 8 or 50 mV more oxidizing glutathione redox potential, E(hc) (GSSG/2GSH), respectively. In contrast, N-acetyl-l-cysteine (NAC) treatment in H9c2 cells, or overexpression of either the glutamate cysteine ligase (GCL) catalytic subunit (GCLC) or GCL modifier subunit (GCLM) in human embryonic kidney 293 T (HEK293T) cells, led to 3- to 4-fold increase of GSH and caused 7 or 12 mV more reducing E(hc), respectively. This condition paradoxically increased the level of mitochondrial oxidation, as demonstrated by redox shifts in mitochondrial roGFP and Trx2. Lastly, either NAC treatment (EC(50) 4 mM) or either GCLC or GCLM overexpression exhibited increased cytotoxicity and the susceptibility to the more reducing milieu was achieved at decreased levels of ROS. Taken together, our findings reveal a novel mechanism by which GSH-dependent reductive stress triggers mitochondrial oxidation and cytotoxicity.-Zhang, H., Limphong, P., Pieper, J., Liu, Q., Rodesch, C. K., Christians, E., Benjamin, I. J. Glutathione-dependent reductive stress triggers mitochondrial oxidation and cytotoxicity.

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the Native Vote for 2012: Igniting the Native Revolution in the Rise to Power
A close examination of the Native American vote in the United States in the national elections of 2012 and the Native perspective of what it means to Indian Country THE NATIVE VOTE FOR 2012: IGNITING THE NATIVE REVOLUTION IN THE RISE TO POWER! By Mike Raccoon Eyes-Native Advocate and Candidate for Richmond CA.
Thu, 29 Dec 2011 08:35:40 GMT
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Country Music’s Final Notes of 2011
Category: Tribute Here is a list of the people in the world of country music for whom the final curtain fell in 2011. Harley Allen (lung cancer, March 30, age 55): the son of bluegrass great Red Allen was a singer and songwriter on his own, having penned such songs as Dierks Bentley’s “My Last Name,
Thu, 29 Dec 2011 00:26:00 CST
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heart disease
mirlotte d asked:


what are some of the positive aspects of a person knowing their status and how they could be affected with some type of heart disease at some point in their life.

Battery Back Up Sump Pumps
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Hoag Honors Two Leading Physicians with Endowed Chairs

• Endowed chairs place Hoag on the level of leading academic institutions who commonly have endowed chair investitures
• Endowed chair positions made possible by Newport Beach couple

(PRWeb December 23, 2011)

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CDC - National Heart Disease and Stroke Prevention Program …
CDC National Heart Disease and Stroke Prevention Program California Capacity Building. In 2007, the California Department of Health Services received CDC …
Tue, 13 Dec 2011 06:11:00 GMT
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Christmas meditation
But Mary treasured up all these things, pondering them in her heart. (Luke 2:19)In the process of maturing in one’s thoughts about the Christian faith, it is possible to go back and forth between Christmas and Easter trying to decide which is the most important day for the Church. For a child, of co
Sat, 24 Dec 2011 22:17:00 CST
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Surprise as scientists find Viagra makes heart relax - Telegraph.co.uk

Telegraph.co.uk

Surprise as scientists find Viagra makes heart relax
Telegraph.co.uk
Viagra has a similar effect on blood vessels, which is why it was originally developed as a treatment for high blood pressure and heart disease. The drug's active ingredient, sildenafil, inhibits an enzyme involved in the mechanism that regulates blood
Viagra treats heart failure?HealthJockey.com
Now, Viagra good for your heart?Hindustan Times
Sildenafil found to alleviate heart problemsLabmate Online
Daily Mail
all 31 news articles »
Fri, 23 Dec 2011 14:34:31 GMT
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“How to Lower Cholesterol Without Drugs”, a New Healthy Living Guide Offered by Solana Health

"How to Lower Cholesterol Without Drugs" is a just-released, free healthy living guide that details a 7-step approach to lowering Cholesterol and Triglyceride levels without prescription drugs.

(PRWeb December 20, 2011)

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drppanda: ?????? ??????????
????, 12:09: From drppanda’s archives: Newer drugs to Control Alzheimer’s Disease Targeting Gene Pr http://t.co/8bAjShSY via @BlogGlue ????, 12:28: From drppanda’s archives: New Drug Approved for Clostridium Diarrhoea http://t.co/BisCTnWt via @BlogGlue ????, 12:45: From drppanda’s archives: …
Sun, 13 Nov 2011 03:00:00 GMT
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[MG-132 enhances MSCs survival and IL-10 secretion under hypoxia and serum deprivation condition].

Sheng Li Xue Bao. 2011 Dec 25; 63(6): 525-32
Li ZW, Fu R, Zhao YR, Zhao C, Li ZY

Bone marrow-derived mesenchymal stem cells (MSCs) have emerged as attractive candidates for cellular therapies for heart and other organ-system disorders. However, a major dilemma in stem cell therapy for ischemic heart diseases is the low survival of transplanted cells in the ischemic and peri-infarcted region. In this study, MSCs were treated by hypoxia and serum deprivation (H/SD) to mimic the ischemic microenvironment of infarcted hearts where MSCs were transplanted. The effects of proteasome inhibitor MG-132 on H/SD-induced apoptosis and paracrine effects were investigated. Apoptosis of MSCs was detected by Annexin V-FITC flow cytometric analysis. Transcriptional levels of IL-1β, TNF-α and IL-10 were examined by real-time PCR. The nuclear translocation of NF-κBp65 was assessed by immunocytochemical staining. Translational changes of IL-1β and TNF-α were detected by Western blot. The secretion of IL-10 from MSCs was examined by ELISA assay. The results showed that MG-132 could effectively suppress H/SD-induced MSCs apoptosis. Furthermore, the induced IL-1β and TNF-α transcription was also inhibited by MG-132 treatment, which may be due to the inhibition of NF-κBp65 nuclear translocation by MG-132. Importantly, MG-132 effectively enhanced H/SD-induced transcription and secretion of IL-10, which is an important paracrine factor from MSCs. Our findings suggest that pretreatment of MSCs by MG-132 before cell transplantation may be an effective strategy to improve cell survival and enhance paracrine effects of MSCs.

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Interactive Sites on Medical Information
This site is from the National Library of Medicine which is under the National Institutes of Health and, as such, is from the U.S. government. It is one of the best sites for medical explanations. Besides…… US taxpayers pay for it! Highly recommend that you keep this for further reference. It ju
Sat, 24 Dec 2011 02:47:00 CST
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Heart Disease Study Highlights Scottish Ethnic Groups Most At Risk: Scots of Pakistani origin are 50 per cent mo… http://t.co/crE62GlX
Heart Disease Study Highlights Scottish Ethnic Groups Most At Risk: Scots of Pakistani origin are 50 per cent mo… http://t.co/crE62GlX
iamdluhansa@twitter.com (Dody Luhansa)
Sat, 24 Dec 2011 09:31:11 +0000
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New evidence on Vitamin D, cancer and heart disease - Consumer Reports.org
Taking vitamin D with calcium supplements reduces fracture risk, especially for institutionalized seniors, but whether the sunshine vitamin prevents cancer is uncertain, according to a systematic review of the medical research published earlier this week …
2011-12-23T19:28:08Z
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Increase in Resting Heart Rate Over Time Linked to Heart Disease Death
Title: Increase in Resting Heart Rate Over Time Linked to Heart Disease Death Category: Health News Created: 12/21/2011 11:01:00 AM Last Editorial Review: 12/21/2011
Wed, 21 Dec 2011 21:14:54 -0800
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Business Wire - Research and Markets: Congenital Heart Disease - Pipeline Review, H2 2011
December 1, 2011 —

DUBLIN — Research and Markets (
Thu, 01 Dec 2011 00:00:00 PST
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Christmas Health Advice From NHS Direct

NHS Direct has identified the most common winter health problems and developed a range of online health and symptom checkers to help people get advice quickly and easily over the Christmas period.

(PRWeb December 21, 2011)

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Fish oil - How does it reduce plasma triglycerides?
Publication Date: 2011 Oct 25 PMID: 22041134Authors: Shearer, G. C. - Savinova, O. V. - Harris, W. S.Journal: Biochim Biophys ActaLong chain omega-3 fatty acids (FAs) are effective for reducing plasma triglyceride (TG) levels. At the pharmaceutical dose, 3.4g/day, they reduce plasma TG by about 25-50% …
Sat, 12 Nov 2011 16:31:00 GMT
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Pesticide Heart

Filed Under heart disease | Comments Off

Healthy Food Expert Chef Gen Anderson Offers Up Delicious Recipe Tips for a Heart-Healthy Holiday Season

Chef Gen, creator and host of the TV cooking series Gen’s Guiltless Gourmet, takes a stand against heart disease and high cholesterol this holiday season. Chef Gen offers expert recipe tips on how to make your holiday favorites high in flavor and low in cholesterol.

(PRWeb December 17, 2011)

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Breast cancer genes may cause heart disease - CBC
Women who are at higher risk of breast cancer may have another threat to contend with: heart disease, suggests new Canadian research. The BRCA1 And BRCA2 genes, which normally regulate the growth of breast and ovarian tumours, are mutated in some women. In …
2011-12-20T22:02:00Z
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Pesticide Heart
Exposure to environment toxins increases the risk for plaque ridden heart arteries.
Sun, 13 Nov 2011 03:48:00 GMT
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Increase in resting heart rate over 10-year period linked with increased risk of heart disease death
In a study that enrolled nearly 30,000 apparently healthy men and women, those who had an increase in their resting heart rate over a 10-year period had an increased risk of death from all causes and from ischemic heart disease, according to a study in the December 21 issue of JAMA. Some evidence in
Wed, 21 Dec 2011 01:42:00 CST
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Color Doppler imaging of the ophthalmic artery in patients with chronic heart failure.

Arq Bras Oftalmol. 2011 Oct; 74(5): 326-9
Almeida-Freitas DB, Meira-Freitas D, Melo LA, Paranhos A, Iared W, Ajzen S

Purpose: To evaluate the ophthalmic artery hemodynamics in patients with chronic heart failure. Methods: Doppler parameters of ophthalmic artery of 18 patients with chronic heart failure in different stages of the disease were compared with 21 healthy volunteers (control group). These parameters were also correlated with echocardiographic assessments and clinical cardiologic status. Results: Mean diastolic velocity was 5.14 ± 2.4 cm/s in the chronic heart failure group and 7.44 ± 3.5 cm/s in the control group (p=0.007). Mean resistance index of the ophthalmic artery was 0.76 ± 0.08 in the chronic heart failure group and 0.70 ± 0.08 in the control group (p=0.04). Mean systolic velocity of the ophthalmic artery was 22.03 ± 7.7 cm/s in the chronic heart failure group and 25.32 ± 9.2 cm/s in the control group (p=0.24). There was a negative correlation between the resistance index of the ophthalmic artery and systemic blood pressure of patients with chronic heart failure (r= -0.47, p=0.007). Diastolic velocity of the ophthalmic artery correlated positively with systemic blood pressure (r=0.44, p=0.02). Conclusion: Lower diastolic velocity and higher resistance index were observed in the ophthalmic artery of chronic heart failure patients when compared to the control group, which probably reflects the presence of orbital vasoconstriction in response to low cardiac output. Therefore, the influence of these findings on the structure and function of the optic nerve head deserves investigation.

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heart disease
Anthony and Danielle asked:


> Volunteers are needed for a research study looking at the effect of fats on vascular health in women.
> Eligible women must be age 18-50, in good health, and overweight or carry extra weight in the midsection.
> Diabetes, heart disease or stroke are exclusions.

So I have a 3rd degree heart block would this mean I am not eligible of would it matter? The only symptom i have is a lower heart rate buts is not life threatening.

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